GUTHRIE TEST
GYNAECOMASTIA
Guthrie test
A blood test performed
routinely on a heel-prick blood sample
taken from babies between the 8th and
14th day after birth to check for the
inherited disorder
phenylketonuria.
GUTHRIE TEST
COLLECTING SAMPLE FOR
GUTHRIE TEST
gynaecology
The
medical
speciality
concerned with the female
reproductive
tract.
Gynaecology deals with
contra-
ception
, the investigation and treatment
of menstrual problems (see
menstru-
ation, disorders
of
),
sexual problems,
infertility
, problems relating to the
meno-
pause
, and disorders such as uterine
fibroids
and
ovarian cysts.
Gynaecology
also covers disorders of early pregnan-
cy, such as recurrent
miscarriage.
gynaecomastia
Enlargement of one or
both
breasts
in the male, due, in some
cases, to an excess of the female sex
hormone
oestrogen
in the blood.
Mild, temporary gynaecomastia can
occur at birth as a result of maternal hor-
mones, and it is common at
puberty
.
Gynaecomastia developing in later life
may be due to chronic liver diseases
such as
cirrhosis.
Hormone secreting
tumours such as pituitary or testicular
tumours may also be a cause.
Adult gynaecomastia, which some-
times occurs in only one breast, can
also occur when synthetic hormones and
some drugs, such as
digoxin, spirono-
lactone,
and
cimetidine,
change the
balance of sex hormones. Rarely, a dis-
crete lump that develops on one breast
may be due to a male breast cancer.
Investigation may involve
blood tests.
If
cancer is suspected, a
biopsy
will be
performed. Treatment depends on the
cause. If a drug is responsible, an alter-
native will be prescribed if possible. If
there is no underlying disease, swelling
usually subsides without treatment.
Cosmetic surgery may be considered in
severe cases (see
mammoplasty).
G
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